DNA‐based typing methods are increasingly important for the characterisation of bacteria. They are used to monitor the epidemiology of pathogens with public health significance and also to help understand the evolution and population biology of bacteria. However, these methods require accuracy and reproducibility and are often of a high‐throughput nature. Laboratory automation is therefore the key to the successful implementation of such methods. This review describes the impact of automation on DNA‐based typing methods, particularly multi‐locus sequence typing (MLST), and the (...) method components that can be automated. BioEssays 24:858–862, 2002. © 2002 Wiley Periodicals, Inc. (shrink)

We conduct an experiment with 459 nonprofessional investors to examine whether they evaluate companies differently based on management’s stated purpose for undertaking corporate social responsibility activities in the presence versus absence of a company-specific negative event. Specifically, we vary whether or not management intends to achieve financial returns from CSR activities in addition to promoting social good. We address investors’ decision processes by investigating whether their judgments are mediated by perceptions of future cash flows and/or the underlying ethical culture of (...) the company. Results show that absent a negative event, investment judgments are stronger when CSR activities are intended to achieve financial returns, through expectations of higher future cash flows. However, when a negative event occurs, we find a moderating effect of independent assurance of CSR disclosures. When disclosures are not assured, investors prefer CSR undertaken only for societal benefit, mediated by perceptions of a stronger ethical culture. However, when disclosures are assured, ethical culture is viewed similarly regardless of management’s intention to achieve financial returns from CSR activities. This suggests that management’s willingness to obtain independent assurance on disclosures is viewed as a positive ethical signal. Thus, assurance complements disclosure of CSR activities by contributing to protection against the impact of negative events. (shrink)

This essay critically comments on Contingent Future Persons (1997), an anthology of thirteen papers on the same topic as Obligations to Future Generations (1978), namely, the morality of decisions affecting the existence, number and identity of future persons. In my discussion, I identify the basic point of dispute between R. M. Hare and Michael Lockwood on potentiality; I criticize Nick Fotion's thesis that the Repugnant Conclusion is too far-fetched to be philosophically valuable; I object to Clark Wolf's "Impure Consequentialist Theory (...) of Obligation"; and I discuss the Non-Identity Problem in connection with essays by Robert Elliot and Ingmar Persson. (shrink)

Computationalism, the notion that cognition is computation, is a working hypothesis of many AI researchers and Cognitive Scientists. Although it has not been proved, neither has it been disproved. In this paper, I give some refutations to some well-known alleged refutations of computationalism. My arguments have two themes: people are more limited than is often recognized in these debates; computer systems are more complicated than is often recognized in these debates. To underline the latter point, I sketch the design and (...) abilities of a possible embodied computer system. (shrink)

With the entry-level student in mind, Stuart Brown guides the reader through three main topics: whether or not there is life after death; whether or not there is a powerful, beneficent intelligence controlling the universe; and the nature and appropriate defence of religious belief or faith. Each chapter is linked to readings by commentators on religion and belief, such as David Hume, John Hick, Richard Dawkins and William James. Key features also include activities and exercises, chapter summaries and guides (...) to further reading. (shrink)

Cognitive agents, whether human or computer, that engage in natural-language discourse and that have beliefs about the beliefs of other cognitive agents must be able to represent objects the way they believe them to be and the way they believe others believe them to be. They must be able to represent other cognitive agents both as objects of beliefs and as agents of beliefs. They must be able to represent their own beliefs, and they must be able to represent beliefs (...) as objects of beliefs. These requirements raise questions about the number of tokens of the belief representation language needed to represent believers and propositions in their normal roles and in their roles as objects of beliefs. In this paper, we explicate the relations among nodes, mental tokens, concepts, actual objects, concepts in the belief spaces of an agent and the agent's model of other agents, concepts of other cognitive agents, and propositions. We extend, deepen, and clarify our theory of intensional knowledge representation for natural-language processing, as presented in previous papers and in light of objections raised by others. The essential claim is that tokens in a knowledge-representation system represent only intensions and not extensions. We are pursuing this investigation by building CASSIE, a computer model of a cognitive agent and, to the extent she works, a cognitive agent herself. CASSIE's mind is implemented in the SNePS knowledge-representation and reasoning system. (shrink)

This essay is concerned with a cluster of related problems which arise for an understanding of religious belief. In my treatment of them I have confined myself to examples drawn almost entirely from the Christian religion. I have accepted this restriction more out of necessity than partiality. It is difficult enough for a European philosopher to avoid unintentionally caricaturing that religion. The risk of his misrepresenting religions which have little influence his own culture must be even greater. I have, however, (...) tried to make a virtue out of this restriction by addressing myself to some issues which have been of particular concern to Christian thinkers in recent years. But I hope that the bearing of my treatment of them on religious belief in general will be apparent. For few of them are peculiar to the Christian religion. (shrink)

This paper develops a synthesis of three basic societal dimensions. These three qualify as basic dimensions by virtue of being collectively inclusive, mutually exclusive to a higher degree than any alternative dimensions we have explored, and universally applicable, i.e., to all social situations. We take the six transact dimensions to be such a set. Of these six we here develop a synthesis of three (acts, people, and time) which we take to be most basic, not in the sense of relative (...) importance to human life and welfare, but in the sense of being completely mutually exclusive, of being explicitly as well as implicitly necessary in the modelling of a very large proportion of social situations, and of being not at all elusive when observed as here in all-or-none units for the acts, “noses counted” for the people, and discrete units of time. For these reasons we consider this set of dimensions especially suitable for first attempts at synthesized rational and predictive models (as distinct from purely analytical, empirical and descriptive models). It is anticipated, however, that as initial efforts increase our scientific skill, essentially the same modelbuilding techniques will be applicable when the “trickiest” or most compounded of the transact dimensions, namely values and circumstances, are also dealt with. Other systems of synthesized, predictive models which we are exploring are described briefly in a later note. (shrink)

This paper outlines some of the moral issues I faced when working in the field with homeless children and children with cerebral palsy. Bill Bunge argues that the 'immediacy' of fieldwork requires...

A reply to Stuart Brown on how to understand the concept of learning.

It is true that Hegelian historicism has indeed led to a dominant ethos of moral relativism bound up with the belief that individual self-actualization is the highest value, thus creating a society that is, in the phrase of H. Tristram Engelhardt, Jr. “after God.” Nevertheless, this egocentric and nihilistic relativism exists alongside a robust and militant moral totalitarianism enforced by the modern clerisy of the media, multi-national corporations, and government bureaucrats, that is, a “managerial elite.” This article argues that the (...) transcendental idealism of Kant and the subsequent historicization of Kant’s dialectic by Hegel has served to reconceptualize the older, Baconian view of science, creating the idea that scientific progress is moving toward the goal of a future perfection of absolute rational unity. The a priori rational structure of reality that makes science possible is not a Platonic Ideal, but something that unfolds within history. This is what allowed Marx to conceive of dialectical materialism as a science, and this is what allows the managerial elite of the present to claim a scientific and objective basis for their programs while at the same time using the tools of historical and cultural criticism to relativize and historicize the claims of all competing moral and social “constructs.”. (shrink)

Having read Prof. Housman's article in the Classical Quarterly of October 1907, it seemed to me worth while, when I was in Madrid last year, to examine the MS of Manilius, Matritensis 31, in those places where Prof. Housman notes that the testimony of Loewe and of Mr Ellis disagree, with the result that I have found Loewe's account of the reading, as given by Prof. Housman, to be correct in all places except the following.

SNePS, the Semantic Network Processing System 45, 54], has been designed to be a system for representing the beliefs of a natural-language-using intelligent system (a \cognitive agent"). It has always been the intention that a SNePS-based \knowledge base" would ultimatelybe built, not by a programmeror knowledge engineer entering representations of knowledge in some formallanguage or data entry system, but by a human informing it using a natural language (NL) (generally supposed to be English), or by the system reading books or (...) articles that had been prepared for human readers. Because of this motivation, the criteria for the development of SNePS have included: it should be able to represent anything and everything expressible in NL; it should be able to represent generic, as well as speci c information; it should be able to use the generic and the speci c information to reason and infer information implied by what it has been told; it cannot count on any particular order among the pieces of information it is given; it must continue to act reasonably even if the information it is given includes circular de nitions, recursive rules, and inconsistent information. (shrink)

‘Der Text der Tragodien des Seneca ist in zwei Rezensionen iiberliefert.Die bessere ist vertreten durch die Haupths. Laur. 37, 13 s. xi/xii.… Zu der schlechteren, stark verfalschten Rezension gehoren die iibrigen Hss., von denen keine iiber die Mitte des 14. Jahrhunderts zuriickgeht.’.

Stuart C. Brown; VII—Intentionality without Grammar, Proceedings of the Aristotelian Society, Volume 65, Issue 1, 1 June 1965, Pages 123–146, https://doi.org/10.

European philosophy from the late seventeenth century through most of the eighteenth is broadly conceived as the "Enlightenment," a period of empricist reaction to the great seventeeth century Rationalists. This volume begins with Herbert of Cherbury and the Cambridge Platonists and with Newton and the early English Enlightenment. Locke is a key figure, as a result of his importance both in the development of British and Irish philosophy and because of his seminal influence in the Enlightenment as a whole. British (...) Philosophy and the Age of the Enlightenment includes discussion of the Scott Enlightenment and its influence on the German Aufklaring , and consequently on Kant. The French Enlightenment, which in turn affected the late radical Enlightenment, especially Bentham, is also considered here. This survey brings together clear, authorative chapters from leading experts and provides a scholarly introduction to this period in the history of philosophy. It includes a glossary of technical terms and a chronological table of important political, philosophical, scientific and other cultural events. (shrink)

No one probably feels tempted to deny that our best authority for the text of the Tragedies is the Etruscus, E , but the authority relatively due to the interpolated tradition A is still a matter of dispute. Leo indeed professed to deny all authority to the evidence of A, even where E is manifestly corrupt. But we should be justified in doing this only if the interpolator of A had based his edition on the text of E, and the (...) text of E had suffered no corruptions subsequent to the making of the A edition. That this is so there is not the least reason to suppose. Peiper therefore was right in requiring for his apparatus criticus an account of the pure A text, though neither he nor Richter took the trouble to search out the oldest and best MSS of the A tradition out of the three hundred or more available. (shrink)

The Bohr-Heisenberg scheme, which forms the basis of any current version of the standard or Copenhagen interpretation of quantum mechanics, is shown to be internally inconsistent. Although the inconsistencies demonstrated here are directly relatable to Einstein's opinion that it is unsatisfactory to interpret physical theory solely in terms of the knowledge gained from experimental outcomes, it is nevertheless shown that Einstein's view requires important modification. The implications of the Bohr-Heisenberg schem's self-inconsistency are discussed in relation to Bell's theorem and Aspect's (...) experiments. (shrink)